Journals and Research

Research and education are foundational to the mission of Bayfront Health and our Digestive Health Institute. As frequent contributors to leading publications on gastroenterology and endoscopy, our physicians share their research and clinical insights with a national and international community of colleagues.

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Author(s) Title Description Publish Date
Hira I Cheema, Benjamin Tharian Big Brother Is Watching Artificial Intelligence in Endoscopy - Hype or Reality Artificial intelligence (AI) has become a part of many image-based specialties, such as radiology and pathology, as well as medical specialties in which "oscopy" is the key to current practice. In gastroenterology, for example, AI is being explored as an aid to endoscopists to visually distinguish p... 2/6/2024
Hira Imad Cheema, Benjamin Tharian, Sumant Inamdar, Mauricio Garcia-Saenz-de-Sicilia, Cem Cengiz Recent advances in endoscopic management of gastric neoplasms The development and clinical application of new diagnostic endoscopic technologies such as endoscopic ultrasonography with biopsy, magnification endoscopy, and narrow-band imaging, more recently supplemented by artificial intelligence, have enabled wider recognition and detection of various gastric ... 6/5/2023
Ishani Shah, Andy Silva-Santisteban, Katharine A Germansky, Arvind Trindade, Kara L Raphael, Vladimir Kushnir, Rishi Pawa, Girish Mishra, Jiannis Anastasiou, Sumant Inamdar, Benjamin Tharian, Mohammad Bilal, Mandeep S Sawhney Pancreatic Cancer Screening for At-Risk Individuals Pancreas Scan Study Yield, Harms, and Outcomes From a Prospective Multicenter Study INTRODUCTION: Guidelines endorse pancreatic cancer screening in genetically susceptible individuals. We conducted a prospective, multicenter study to determine yield, harms, and outcomes of pancreatic cancer screening. 5/4/2023
Abhilash Perisetti, Benjamin Tharian, Tony C Tham, Hemant Goyal Editorial Recent updates in advanced gastrointestinal endoscopy No abstract 1/23/2023
Alessandro Paniccia, Patricio M Polanco, Brian A Boone, Abigail I Wald, Kevin McGrath, Randall E Brand, Asif Khalid, Nisa Kubiliun, Anne Marie O'Broin-Lennon, Walter G Park, Jason Klapman, Benjamin Tharian, Sumant Inamdar, Kenneth Fasanella, John Nasr, Jennifer Chennat, Rohit Das, John DeWitt, Jeffrey J Easler, Benjamin Bick, Harkirat Singh, Kimberly J Fairley, Savreet Sarkaria, Tarek Sawas, Wasseem Skef, Adam Slivka, Anna Tavakkoli, Shyam Thakkar, Victoria Kim, Hendrikus Dutch Vanderveldt, Allyson Richardson, Michael B Wallace, Bhaumik Brahmbhatt, Megan Engels, Charles Gabbert, Mohannad Dugum, Samer El-Dika, Yasser Bhat, Sanjay Ramrakhiani, Gennadiy Bakis, Daniil Rolshud, Gordon Millspaugh, Thomas Tielleman, Carl Schmidt, John Mansour, Wallis Marsh, Melanie Ongchin, Barbara Centeno, Sara E Monaco, N Paul Ohori, Sigfred Lajara, Elizabeth D Thompson, Ralph H Hruban, Phoenix D Bell, Katelyn Smith, Jennifer B Permuth, Christopher Vandenbussche, Wayne Ernst, Maria Grupillo, Cihan Kaya, Melissa Hogg, Jin He, Christopher L Wolfgang, Kenneth K Lee, Herbert Zeh, Amer Zureikat, Marina N Nikiforova, Aatur D Singhi Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts CONCLUSIONS: PancreaSeq was not only sensitive and specific for various pancreatic cyst types and advanced neoplasia arising from mucinous cysts, but also reveals the diversity of genomic alterations seen in pancreatic cysts and their clinical significance. 10/9/2022
Jennifer L Maranki, Steven D Schwaitzberg, Reem Z Sharaiha, Vladimir M Kushnir, Dilhana S Badurdeen, Vivek Kumbhari, Victoria Gómez, Nikhil A Kumta, Jerome D Waye, Jose Nieto, Michael B Ujiki, Petros C Benias, Larry S Miller, Prashant Kedia, Paul Tarnasky, Abraham Mathew, John M Levenick, Sumant Inamdar, Benjamin Tharian, Yanina Nersesova, Lydia Fredell, Sonya Serra, Michael L Kochman Challenges of developing and executing a multi-site registry for a novel device with evolving indications for use CONCLUSIONS: The Prospective Registry for Trans-Orifice Endoscopic Suturing Applications (ES Registry) was an effective Phase 4, postmarketing registry aimed at capturing pragmatic, real-world use of a novel device. These findings serve to solidify the role of endoscopic suturing in clinical practic... 8/3/2022
Hira Cheema, Saikiran Raghavapuram, Iman Boston, Cem Cengiz, Jiannis Anastasiou, Sumant Inamdar, Benjamin Tharian Resection of subepithelial lesions by a novel technique Band endoscopic full-thickness resection No abstract 8/1/2022
Hemant Goyal, Sonali Sachdeva, Syed Ali Amir Sherazi, Shweta Gupta, Abhilash Perisetti, Aman Ali, Saurabh Chandan, Benjamin Tharian, Neil Sharma, Nirav Thosani Early prediction of post-ERCP pancreatitis by post-procedure amylase and lipase levels A systematic review and meta-analysis Background and study aims Post-ERCP pancreatitis (PEP) is the most common complication attributed to the procedure, its incidence being approximately 9.7 %. Numerous studies have evaluated the predictive efficacy of post-procedure serum amylase and lipase levels but with varied procedure-to-test ti... 7/18/2022
Hira I Cheema, Saikiran Raghavapuram, Iman Boston, Thomas Augustine, Benjamin Tharian A Case of Duodenal Spot Diagnosis Pseudomelanosis duodeni is a rare finding usually described as a black/brown speckled or tattooed appearance of the intestinal mucosa. Although an incidental finding, it has been associated with different medications and chronic medical conditions such as diabetes mellitus and chronic renal failure.... 7/8/2022
Hira I Cheema, Russell Roark, Seemeen Hassan, Kalyan Chakrala, Benjamin Tharian, Jiannis Anastasiou Comparison Between Intravenous and Intramuscular Octreotide in the Management of Heydes Syndrome Heyde's syndrome is defined as a triad of aortic stenosis, anemia due to angiodysplasia-related bleeding, and von Willebrand syndrome type 2A. It is a rare disease and a diagnostic challenge. Treatment modalities include symptomatic management, blood transfusions, aortic valve replacement, and medic... 7/5/2022
Hemant Goyal, Sara Larsen, Abhilash Perisetti, Nikolaj Birk Larsen, Lotte Klinten Ockert, Sven Adamsen, Benjamin Tharian, Nirav Thosani Gastrointestinal endoscope contamination rates - elevators are not only to blame a systematic review and meta-analysis Background and study aims Duodenoscopes that are contaminated due to inadequate reprocessing are well-documented. However, studies have demonstrated poor reprocessing of other kinds of endoscopes as well, including echoendoscopes, gastroscopes, and colonoscopes. We estimated the contamination rate b... 6/13/2022
Hemant Goyal, Syed Ali Amir Sherazi, Shweta Gupta, Abhilash Perisetti, Ikechukwu Achebe, Aman Ali, Benjamin Tharian, Nirav Thosani, Neil R Sharma Application of artificial intelligence in diagnosis of pancreatic malignancies by endoscopic ultrasound a systemic review CONCLUSION: AI reported a high sensitivity with high specificity and accuracy to diagnose PC, differentiate PC from CP, and differentiate benign from malignant IPMN when used with EUS. 5/5/2022
Shorabuddin Syed, Adam Jackson Angel, Hafsa Bareen Syeda, Carole France Jennings, Joseph VanScoy, Mahanazuddin Syed, Melody Greer, Sudeepa Bhattacharyya, Meredith Zozus, Benjamin Tharian, Fred Prior The h-ANN Model Comprehensive Colonoscopy Concept Compilation Using Combined Contextual Embeddings Colonoscopy is a screening and diagnostic procedure for detection of colorectal carcinomas with specific quality metrics that monitor and improve adenoma detection rates. These quality metrics are stored in disparate documents i.e., colonoscopy, pathology, and radiology reports. The lack of integrat... 4/4/2022
Shorabuddin Syed, Adam Jackson Angel, Hafsa Bareen Syeda, Carole Franc Jennings, Joseph VanScoy, Mahanazuddin Syed, Melody Greer, Sudeepa Bhattacharyya, Shaymaa Al-Shukri, Meredith Zozus, Fred Prior, Benjamin Tharian TAX-Corpus Taxonomy based Annotations for Colonoscopy Evaluation Colonoscopy plays a critical role in screening of colorectal carcinomas (CC). Unfortunately, the data related to this procedure are stored in disparate documents, colonoscopy, pathology, and radiology reports respectively. The lack of integrated standardized documentation is impeding accurate report... 3/18/2022
Hemant Goyal, Abhilash Perisetti, Sumant Inamdar, Benjamin Tharian, Jiannis Anastasiou Artificial Intelligence-Assisted Optical Biopsies of Colon Polyps Hype or Reality No abstract 3/14/2022
Abhilash Perisetti, Hemant Goyal, Rachana Yendala, Saurabh Chandan, Benjamin Tharian, Ragesh Babu Thandassery Sarcopenia in hepatocellular carcinoma Current knowledge and future directions Liver cancer is the second most occurring cancer worldwide and is one of the leading causes of cancer-related deaths. Hepatocellular carcinoma (HCC) is the most common (80%-90%) type among malignant liver cancers. Sarcopenia occurs very early in HCC and can predict and provide an opportunity to impr... 2/7/2022
Fredy Nehme, Hemant Goyal, Abhilash Perisetti, Benjamin Tharian, Neil Sharma, Tony C Tham, Rajiv Chhabra The Evolution of Device-Assisted Enteroscopy From Sonde Enteroscopy to Motorized Spiral Enteroscopy The introduction of capsule endoscopy in 2001 opened the last "black box" of the gastrointestinal tract enabling complete visualization of the small bowel. Since then, numerous new developments in the field of deep enteroscopy have emerged expanding the diagnostic and therapeutic armamentarium again... 1/10/2022
Rupinder Mann, Hemant Goyal, Abhilash Perisetti, Saurabh Chandan, Sumant Inamdar, Benjamin Tharian Endoscopic ultrasound-guided vascular interventions Current insights and emerging techniques Endoscopic ultrasound (EUS) is one of the significant breakthroughs in the field of advanced endoscopy. In the last two decades, EUS has evolved from a diagnostic tool to a real-time therapeutic modality. The luminal gastrointestinal (GI) tract provides a unique opportunity to access multiple vascul... 11/18/2021
Hemant Goyal, Jonathan Kopel, Bojana Ristić, Abhilash Perisetti, Jiannis Anastasiou, Saurabh Chandan, Benjamin Tharian, Sumant Inamdar The pancreas and COVID-19 a clinical conundrum With the progression of the COVID-19 pandemic, the classic manifestations of COVID-19 (e.g., persistent fever, dry cough, pneumonia, and acute respiratory distress syndrome in the severe disease) have expanded to include less common complications of the extrapulmonary organs. Recent evidence has sho... 11/17/2021
Hemant Goyal, Syed A A Sherazi, Rupinder Mann, Zainab Gandhi, Abhilash Perisetti, Muhammad Aziz, Saurabh Chandan, Jonathan Kopel, Benjamin Tharian, Neil Sharma, Nirav Thosani Scope of Artificial Intelligence in Gastrointestinal Oncology Gastrointestinal cancers are among the leading causes of death worldwide, with over 2.8 million deaths annually. Over the last few decades, advancements in artificial intelligence technologies have led to their application in medicine. The use of artificial intelligence in endoscopic procedures is a... 11/13/2021
Pauline M C Stassen, Pieter Jan F de Jonge, Marco J Bruno, Arjun D Koch, Arvind J Trindade, Petros C Benias, Divyesh V Sejpal, Uzma D Siddiqui, Christopher G Chapman, Edward Villa, Benjamin Tharian, Sumant Inamdar, Joo Ha Hwang, Monique T Barakat, Iman Andalib, Monica Gaidhane, Avik Sarkar, Haroon Shahid, Amy Tyberg, Kenneth Binmoeller, Rabindra R Watson, Andrew Nett, Christoph Schlag, Mohamed Abdelhafez, Mireen Friedrich-Rust, Alexander Schlachterman, Austin L Chiang, David Loren, Thomas Kowalski, Michel Kahaleh Safety and efficacy of a novel resection system for direct endoscopic necrosectomy of walled-off pancreas necrosis a prospective, international, multicenter trial CONCLUSIONS: The new PED system seems to be a safe and effective treatment tool for WOPN, resulting in fewer interventions and lower hospital duration when compared with published data on using conventional instruments. Randomized controlled trials comparing the PED system with conventional DEN are ... 9/25/2021
Mark M Aloysius, Hemant Goyal, Niraj James Shah, Abhilash Perisetti, Benjamin Tharian Working with fellows improves adenoma detection rate during screening colonoscopies No abstract 9/17/2021
Shashank Garg, Sumant Inamdar, Benjamin Tharian, Thiruvengadam Muniraj, Harry R Aslanian Education and gastroenterology fellow knowledge about endoscopic mucosal resection of colon adenomas a survey-based study Background and study aims Endoscopic mucosal resection (EMR) is an effective way to remove large (> 2 cm) colon adenomas. Training about it has not been standardized in fellowship programs. This study was aimed at evaluating the education and knowledge of gastroenterology fellows about EMR of color... 8/27/2021
Hemant Goyal, Sonali Sachdeva, Abhilash Perisetti, Rupinder Mann, Saurabh Chandan, Sumant Inamdar, Benjamin Tharian Management of gastrointestinal bleeding during COVID-19 less is more No abstract 8/16/2021
Mark M Aloysius, Hemant Goyal, Niraj J Shah, Kumar Pallav, Nimy John, Mahesh Gajendran, Abhilash Perisetti, Benjamin Tharian Impact of Race and Socioeconomics Disparities on Survival in Young-Onset Colorectal Adenocarcinoma-A SEER Registry Analysis CONCLUSIONS: Survival disparities were found among all races with young-onset colorectal adenocarcinoma. The pattern of SEDH influencing survival was unique to each race. Overall higher income levels, high school education, private insurance, and marital status appeared to be independent factors con... 7/2/2021
Shorabuddin Syed, Benjamin Tharian, Hafsa Bareen Syeda, Meredith Zozus, Melody L Greer, Sudeepa Bhattacharyya, Mahanazuddin Syed, Fred Prior Consolidated EHR Workflow for Endoscopy Quality Reporting Although colonoscopy is the most frequently performed endoscopic procedure, the lack of standardized reporting is impeding clinical and translational research. Inadequacies in data extraction from the raw, unstructured text in electronic health records (EHR) pose an additional challenge to procedure... 5/27/2021
Abhilash Perisetti, Hemant Goyal, Benjamin Tharian The burn of ranitidine recall current insights and mitigation strategies Ranitidine was one of the most commonly used medications for the treatment of gastroesophageal reflux disease. On 1 April 2020, the US Food and Drug Administration requested all manufacturers to immediately withdraw ranitidine from the market because of concern of higher than acceptable levels of N-... 4/19/2021
Jesse Xie, Shashank Garg, Abhilash Perisetti, Benjamin Tharian, Mohammad Hassan Murad, Sumant Inamdar Comparison of Biliary Drainage Techniques for Malignant Biliary Obstruction A Systematic Review and Network Meta-analysis CONCLUSIONS: The available evidence did not favor any intervention for drainage of malignant biliary obstruction across all the outcomes assessed. ERCP with or without EUS should be considered first to allow simultaneous tissue acquisition and biliary drainage. 3/29/2021
Hemant Goyal, Rupinder Mann, Zainab Gandhi, Abhilash Perisetti, Zhongheng Zhang, Neil Sharma, Shreyas Saligram, Sumant Inamdar, Benjamin Tharian Application of artificial intelligence in pancreaticobiliary diseases The role of artificial intelligence and its applications has been increasing at a rapid pace in the field of gastroenterology. The application of artificial intelligence in gastroenterology ranges from colon cancer screening and characterization of dysplastic and neoplastic polyps to the endoscopic ... 3/1/2021
Hemant Goyal, Jonathan Kopel, Abhilash Perisetti, Rupinder Mann, Aman Ali, Benjamin Tharian, Shreyas Saligram, Sumant Inamdar Endobariatric procedures for obesity clinical indications and available options Obesity remains a growing public health epidemic that has increased healthcare costs and related comorbidities. Current treatment guidelines encourage a multidisciplinary approach starting from patient selection, interventions, and long-term follow-up to maintain weight loss. However, these conserva... 2/25/2021
Kemmian D Johnson, Abhilash Perisetti, Hemant Goyal, Ragesh Thandassery, Mahesh Gajendran, Mohammad Aziz, Benjamin Tharian, Sumant Inamdar Liver Biopsy in Pregnancy Two Case Reports and Review of the Literature The etiology of most cases of liver diseases in pregnancy can be diagnosed with a thorough history, physical examination, laboratory values, serology, and noninvasive imaging. However, atypical clinical and laboratory presentations of liver diseases/chemistries require a liver biopsy to render an ac... 1/12/2021
Meir Mizrahi, Yazan Fahmawi, Lindsey Merritt, Manoj Kumar, Benjamin Tharian, Salman Ali Khan, Sumant Inamdar, Neil Sharma, Dushant Uppal, Vanessa M Shami, Mahmood Syed Kashif, Moamen Gabr, Douglas Pleskow, Tyler M Berzin, Ted W James, Michael Croglio, Todd H Baron, Douglas G Adler Luminal-apposing stents for benign intraluminal strictures a large United States multicenter study of clinical outcomes CONCLUSIONS: Using LAMS for treatment of short benign GI strictures is safe and effective. Larger LAMS, such as the new 20 mm in diameter, may have a lower stent migration rate compared to smaller diameter LAMS. 1/8/2021
Abhilash Perisetti, Hemant Goyal, Benjamin Tharian, Sumant Inamdar, Jawahar L Mehta Aspirin for prevention of colorectal cancer in the elderly friend or foe Cancer is the leading cause of death among men and women aged 60-79 years. Colorectal cancer is the third most common cancer in males and the second most common in females, with about 0.8 million deaths worldwide per year. Individuals older than 50 years account for 20-50% of colonic adenomas. Sever... 1/8/2021
Yervant Ichkhanian, Mohammed Barawi, Talal Seoud, Shyam Thakkar, Truptesh H Kothari, Maan El Halabi, Asad Ullah, Wedi Edris, Patrick Aepli, Thomas Kowalski, Brianna Shinn, Reem Z Shariaha, Srihari Mahadev, Jeffrey D Mosko, Gianluca Andrisani, Francesco Maria Di Matteo, Heinz Albrecht, Andrew Q Giap, Shou-Jiang Tang, Yehia M Naga, Erwin van Geenen, Shai Friedland, Benjamin Tharian, Shayan Irani, Andrew S Ross, Laith H Jamil, Daniel Lew, Andrew S Nett, Jad Farha, Thomas M Runge, Manol Jovani, Mouen A Khashab Endoscopic full-thickness resection of polyps involving the appendiceal orifice a multicenter international experience CONCLUSIONS: The FTRD is a promising non-surgical alternative for resecting appendiceal lesions, but appendicitis occurs in 1/6 cases. 1/4/2021
Muhammad Aziz, Chandra Shekhar Dasari, Yousaf Zafar, Rawish Fatima, Hossein Haghbin, Zakaria Abdullah Alyousif, Wade Lee-Smith, Abhilash Perisetti, Ali Nawras, Shashank Garg, Sumant Inamdar, Benjamin Tharian Does timing of endoscopy affect outcomes in patients with upper gastrointestinal bleeding a systematic review and meta-analysis CONCLUSION: Given the outcomes and limitations, our meta-analysis did not demonstrate clear benefit of performing EGD within 24 h of presentation for UGIB (particularly NVB). 11/12/2020
Mahesh Gajendran, Abhilash Perisetti, Muhammad Aziz, Saikiran Raghavapuram, Pardeep Bansal, Benjamin Tharian, Hemant Goyal Inflammatory bowel disease amid the COVID-19 pandemic impact, management strategies, and lessons learned The current outbreak of COVID-19 pandemic caused by SARS-CoV-2 has affected nearly 188 countries. Patients with severe COVID-19 are more commonly elderly and suffer from comorbidities such as hypertension, diabetes mellitus, coronary artery disease, chronic pulmonary disease, obesity, and cancer. In... 11/9/2020
Abhilash Perisetti, Mahesh Gajendran, Chandra Shekhar Dasari, Pardeep Bansal, Muhammad Aziz, Sumant Inamdar, Benjamin Tharian, Hemant Goyal Cannabis hyperemesis syndrome an update on the pathophysiology and management Cannabis hyperemesis syndrome (CHS) is a form of functional gut-brain axis disorder characterized by bouts of episodic nausea and vomiting worsened by cannabis intake. It is considered as a variant of cyclical vomiting syndrome seen in cannabis users especially characterized by compulsive hot bathin... 11/9/2020
Hemant Goyal, Sonali Sachdeva, Abhilash Perisetti, Rupinder Mann, Sumant Inamdar, Benjamin Tharian Hyperlipasemia and Potential Pancreatic Injury Patterns in COVID-19 A Marker of Severity or Innocent Bystander No abstract 11/1/2020
Hemant Goyal, Rupinder Mann, Zainab Gandhi, Abhilash Perisetti, Aman Ali, Khizar Aman Ali, Neil Sharma, Shreyas Saligram, Benjamin Tharian, Sumant Inamdar Scope of Artificial Intelligence in Screening and Diagnosis of Colorectal Cancer Globally, colorectal cancer is the third most diagnosed malignancy. It causes significant mortality and morbidity, which can be reduced by early diagnosis with an effective screening test. Integrating artificial intelligence (AI) and computer-aided detection (CAD) with screening methods has shown pr... 10/20/2020
Hemant Goyal, Abhilash Perisetti, Benjamin Tharian Percutaneous Endoscopic Gastrostomy tube placement in COVID-19 patients Multidisciplinary approach No abstract 10/16/2020
Ji Young Bang, Thomas Rösch, Hyungjin Myra Kim, Shyam Thakkar, Ernesto Robalino Gonzaga, Benjamin Tharian, Sumant Inamdar, Linda S Lee, Patrick Yachimski, Priya Jamidar, Thiruvengadam Muniraj, Christopher DiMaio, Nikhil Kumta, Amrita Sethi, Peter Draganov, Dennis Yang, Talal Seoud, Abhilash Perisetti, Gayatri Bondi, Sachin Kirtane, Robert Hawes, C Mel Wilcox, Richard Kozarek, D Nageshwar Reddy, Shyam Varadarajulu Prospective evaluation of an assessment tool for technical performance of duodenoscopes CONCLUSIONS: The newly developed assessment tool appears reliable and valid for evaluating the technical performance of duodenoscopes. Registration: Identifier: NCT04004533. 10/2/2020
Thomas Augustine, Abhilash Perisetti, Salman Ali Khan, Rodolfo Henrich Lobo, Benjamin Tharian Primary Colonic Lymphoma With Paraneoplastic Hypercalcemia Primary colonic lymphoma is a rare tumor accounting for 0.1%-0.5% of all colorectal malignancies. We describe a 63-year-old man whose initial presentation was altered mental status due to hypercalcemia. Physical examination revealed a hard, right-sided abdominal mass. Abdominal computed tomography s... 9/28/2020
Hemant Goyal, Mahesh Gajendran, Umesha Boregowda, Abhilash Perisetti, Muhammad Aziz, Pardeep Bansal, Sumant Inamdar, Benjamin Tharian Current and future implications of COVID-19 on gastroenterology training and clinical practice The novel coronavirus disease 2019 (COVID-19) pandemic has affected almost every country on the globe, affecting 185 countries with more than 2.6 million cases and 182,000 deaths as of April 22, 2020. The United States (US) has seen an exponential surge in the COVID-19 patients and has become the ep... 9/21/2020
Abhilash Perisetti, Hemant Goyal, Benjamin Tharian, Sumant Inamdar, Shashank Garg Endoscopic resection of multiple large gastric polyps No abstract 9/11/2020
Abhilash Perisetti, Hemant Goyal, Benjamin Tharian Role of TC-325 in GI tumor hemostasis No abstract 8/26/2020
Abhilash Perisetti, Benjamin Tharian, Felicia D Allard, Hemant Goyal, Sumant Inamdar Endoscopic resection of a giant duodenal mass No abstract 6/27/2020
Chiranjeevi Gadiparthi, Abhilash Perisetti, Hari Sayana, Benjamin Tharian, Sumant Inamdar, Andrew Korman Gastrointestinal Bleeding in Patients with Severe SARS-CoV-2 Gastrointestinal symptoms are common and frequently reported in Coronavirus Disease-2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is unclear if SARS-CoV-2 is associated with increased risk of gastrointestinal bleeding (GIB). Nevertheless, GIB in... 6/10/2020
Kemmian D Johnson, Passisd Laoveeravat, Eric U Yee, Abhilash Perisetti, Ragesh Babu Thandassery, Benjamin Tharian Endoscopic ultrasound guided liver biopsy Recent evidence Liver biopsy (LB) is an essential tool in diagnosing, evaluating and managing various diseases of the liver. As such, histopathological results are critical as they establish or aid in diagnosis, provide information on prognosis, and guide the appropriate selection of medical therapy for patients. I... 3/29/2020
Abhilash Perisetti, Matthew Deneke, Ragesh Thandassery, Benjamin Tharian Role of different types of stents in EUS-guided gallbladder drainage No abstract 3/25/2020
Abhilash Perisetti, Passisd Laoveeravat, Sumant Inamdar, Benjamin Tharian, Ragesh Thandassery, Hemant Goyal Hepatitis E virus infection in liver transplant recipients a descriptive literature review Hepatitis E virus infection has been recognized as a rising hepatotropic viral infection in the developing countries but overlooked in the developed countries, due to its lower prevalence. However, hepatitis E virus prevalence is on rise in the liver transplant recipients due to immunosuppression, w... 2/25/2020
Passisd Laoveeravat, Abhilash Perisetti, Mauricio Garcia-Saenz-de-Sicilia, Shashank Garg, Benjamin Tharian Is combining therapy with indomethacin and epinephrine useful for preventing post-ERCP pancreatitis The answer from a meta-analysis No abstract 2/4/2020
Jessica Stout, James D Ireland, Nayana George, Mary Katherine Rude, Ragesh B Thandassery Liver Mass in a Patient With Chronic Hepatitis B Infection No abstract 12/14/2019
Dennis Yang, Hiroyuki Aihara, Yaseen B Perbtani, Andrew Y Wang, Abdul Aziz Aadam, Yutaka Tomizawa, Joo Ha Hwang, Baiming Zou, Nikola S Natov, Amanda Siegel, Milad Pourmousavi Khoshknab, Mouen A Khashab, Saowanee Ngamruengphong, Harshit S Khara, David L Diehl, Thibaut Maniere, Sherif Andrawes, Petros Benias, Nikhil A Kumta, Fariha Ramay, Raymond E Kim, Jason Samarasena, Kenneth Chang, Rintaro Hashimoto, Benjamin Tharian, Sumant Inamdar, Gloria Lan, Amrita Sethi, Michael J Nosler, Abdalaziz Tabash, Mohamed O Othman, Peter V Draganov Safety and efficacy of endoscopic submucosal dissection for rectal neoplasia a multicenter North American experience Background and aims Rectal lesions traditionally represent the first lesions approached during endoscopic submucosal dissection (ESD) training in the West. We evaluated the safety and efficacy of rectal ESD in North America. Methods This is a multicenter retrospective analysis of rectal ESD between ... 12/6/2019
Kemmian D Johnson, Abhilash Perisetti, Benjamin Tharian, Ragesh Thandassery, Priya Jamidar, Hemant Goyal, Sumant Inamdar Endoscopic Retrograde Cholangiopancreatography-Related Complications and Their Management Strategies A Scoping Literature Review Endoscopic retrograde cholangiopancreatography (ERCP) is a well-known procedure with both diagnostic and therapeutic utilities in managing pancreaticobiliary conditions. With the advancements of endoscopic techniques, ERCP has become a relatively safe and effective procedure. However, as ERCP is inc... 12/4/2019
Abhilash Perisetti, Shashank Garg, Sumant Inamdar, Benjamin Tharian Role of face mask in preventing bacterial exposure to the endoscopists face No abstract 10/23/2019
Ujas Patel, Jesse J Xie, Quinton Palmer, Salman Khan, Glenn Murray, Benjamin Tharian An Extraordinary Case of Extranodal Non-Hodgkins Lymphoma Presenting as Common Bile Duct Mass No abstract 8/30/2019
Passisd Laoveeravat, Subhanudh Thavaraputta, Sakolwan Suchartlikitwong, Wasawat Vutthikraivit, Thammasak Mingbunjerdsuk, Arunee Motes, Kenneth Nugent, Abhilash Perisetti, Benjamin Tharian, Sameer Islam, Ariwan Rakvit Optimal sequences of same-visit bidirectional endoscopy Systematic review and meta-analysis CONCLUSION: The present study found that the discomfort score was better in the E-C group. However, there was no difference in polyp and adenoma detection. Therefore, the E-C group is the optimal sequence. 8/2/2019
Abhilash Perisetti, Sumanth Inamdar, Benjamin Tharian Sedation in endoscopic gallbladder drainage in high-risk surgical patients No abstract 7/23/2019
Arvind J Trindade, Petros C Benias, Mohammed Alshelleh, Ahmad N Bazarbashi, Benjamin Tharian, Sumant Inamdar, Neil Sharma, Christina Zelt, Praneet Korrapati, Mohamed Barakat, Divyesh V Sejpal, Marvin Ryou Fine-needle biopsy is superior to fine-needle aspiration of suspected gastrointestinal stromal tumors a large multicenter study Background and study aims There are numerous studies published on the diagnostic yield of the new fine-needle biopsy (FNB) needles in pancreas masses. However, there are limited studies in suspected gastrointestinal stromal tumors (GIST lesions). The aim of this study was to evaluate the diagnostic... 7/16/2019
Benjamin Tharian, Konrad Krall, Xiang Zhu, Nayana George, Michael Chambers, Shyam Varadarajulu, Shantel Hebert-Magee Endosonographer-driven dynamic telecytopathology of pancreatic lesions-a pilot study CONCLUSION: An endosonographer with limited training can examine for specimen adequacy, transmit images, and demonstrate representative cell groups. Larger studies are required though preliminary results are encouraging. 5/3/2019
Abhilash Perisetti, Jonathan Kopel, Abdussalam Shredi, Saikiran Raghavapuram, Benjamin Tharian, Kenneth Nugent Prophylactic pre-esophagogastroduodenoscopy tracheal intubation in patients with upper gastrointestinal bleeding The indications for endotracheal intubation (ETI) during an esophagogastroduodenoscopy (EGD) procedure remain unclear. This study performed a descriptive analysis of patients who underwent prophylactic tracheal intubation during or before an EGD to prevent pulmonary aspiration. We selected patients ... 4/9/2019
Abhilash Perisetti, Saikiran Raghavapuram, Benjamin Tharian Refractory cystic duct stump leak treated with fibrin glue No abstract 4/3/2019
Thomas Augustine, Abhilash Perisetti, Benjamin Tharian Unusual Cause of Upper Gastrointestinal Bleeding in Cirrhosis No abstract 3/24/2019
Saad Khan, John Ramzy, Danae Papachristos, Nayana George, Leon Fisher Ventricular Standstill Following Intravenous Erythromycin and Borderline Hypokalemia Ventricular standstill (VS) is a potentially fatal arrhythmia that is usually associated with syncope, if prolonged and is rarely asymptomatic^([1]). Its mechanism involves either a lack of supraventricular impulse or an interruption in the transmission of these signals from the atria to the ventric... 2/14/2019
Jennifer E Tham, Benjamin Tharian, Patrick B Allen, Gary Spence, Tony C Tham Oesophageal Stents for Potentially Curable Oesophageal Cancer - A Bridge to Surgery For oesophageal cancer patients with potentially curative disease, treatment usually comprises neoadjuvant chemoradiotherapy followed by surgery. Several methods are currently used for nutritional support while patients are undergoing neoadjuvant treatment but these do not relieve dysphagia. Stentin... 1/25/2019
Ji Young Bang, Juan Pablo Arnoletti, Bronte A Holt, Bryce Sutton, Muhammad K Hasan, Udayakumar Navaneethan, Nicholas Feranec, C Mel Wilcox, Benjamin Tharian, Robert H Hawes, Shyam Varadarajulu An Endoscopic Transluminal Approach, Compared With Minimally Invasive Surgery, Reduces Complications and Costs for Patients With Necrotizing Pancreatitis CONCLUSIONS: In a randomized trial of 66 patients, an endoscopic transluminal approach for infected necrotizing pancreatitis, compared with minimally invasive surgery, significantly reduced major complications, lowered costs, and increased quality of life. no: NCT02084537. 11/20/2018
Abhilash Perisetti, Hafiz Khan, Nayana E George, Rachana Yendala, Aamrin Rafiq, Summre Blakely, Drew Rasmussen, Nathan Villalpando, Hemant Goyal Colorectal cancer screening use among insured adults Is out-of-pocket cost a barrier to routine screening CONCLUSION: We found that the limited financial resources within the past 12 mo were significantly associated with colorectal cancer (CRC) non-screening. Patients with risk factors identified in this study should adhere to CRC guidelines and should receive financial help if needed. 9/8/2018
Naga S Addepally, Nayana George, Roberto Martinez-Macias, Mauricio Garcia-Saenz-de-Sicilia, W Ray Kim, Andres Duarte-Rojo Hemoglobin A1c Has Suboptimal Performance to Diagnose and Monitor Diabetes Mellitus in Patients with Cirrhosis CONCLUSION: HbA1c inaccurately represents chronic glycemia in patients with cirrhosis, likely in relation to increased glucose variability. 8/31/2018
Debdeep Banerjee, Saikiran Raghavapuram, Nayana E George, Soheila Korourian, Faysal A Fedda, Abhilash Perisetti, Benjamin Tharian Cholangiocarcinoma Presenting as Linitis Plastica with Unusual Metastases to the Psoas Muscle and Urinary Bladder Cholangiocarcinoma offers poor prognosis. Infrequent sites of metastasis are poorly described and often diagnostically delayed or missed. Bile duct brush cytologies provide poor diagnostic sensitivity/specificity. We present an unusual case of cholangiocarcinoma in a 34-year-old woman with rare dist... 7/25/2018
Debdeep Banerjee, Abhilash Perisetti, Saikiran Raghavapuram, Nayana George, Benjamin Tharian Successful Removal of Proximally Migrated Biliary Stent in a Liver Transplant Patient by Single-Operator Digital Cholangioscopy No abstract 6/29/2018
Saikiran Raghavapuram, Nayana George, Mohit Girotra, Sameer Siddique, Benjamin Tharian Downhill esophageal varices unusual cause of hematemesis No abstract 6/16/2018
Debdeep Banerjee, Saikiran Raghavapuram, Susanne Jeffus, Seamus Murphy, Benjamin Tharian Linitis plastica a harbinger of an unusual cause of gastric wall thickening No abstract 6/16/2018
Kulsum Bano, Mohammad Al-Shoha, Saikiran Raghavapuram, Nayana George, Abhilash Perisetti, Wesley Mallinger, Benjamin Tharian Gastric Cardia Cancer Masquerading as a Fundic Subepithelial Tumor No abstract 6/15/2018
Mohammad Al-Shoha, Urooba Nadeem, Nayana George, Saikiran Raghavapuram, Wesley Mallinger, Benjamin Tharian Verrucous carcinoma of the esophagus-remains a diagnostic enigma No abstract 5/12/2018
Arvind J Trindade, Petros C Benias, Praneet Kurupathi, Benjamin Tharian, Sumant Inamdar, Neil Sharma, Divyesh V Sejpal, Ali A Siddiqui, Douglas G Adler Digital pancreatoscopy in the evaluation of main duct intraductal papillary mucinous neoplasm a multicenter study CONCLUSION: Digital pancreatoscopy should be considered in the diagnostic algorithm of MD-IPMN in patients with a diffusely dilated pancreatic duct and without any focal lesions seen on cross-sectional imaging or EUS. 4/27/2018
Nayana George, Saikiran Raghavapuram, Abhilash Perisetti Abdominal Pain Caused by a Second Gall Bladder and Separate Cystic Duct No abstract 3/25/2018
Abhilash Perisetti, Saikiran Raghavapuram, Benjamin Tharian, Irfan Warraich, Fred Hardwicke, Rubayat Rahman, Edwin Onkendi Pure Squamous Cell Carcinoma of the Gallbladder Masquerading as a Hepatic Mass Gallbladder (GB) carcinomas are adenocarcinomas (AC) in the majority of cases. Adenosquamous carcinoma (ASC) and pure squamous cell carcinoma (SCC) of the gallbladder are rarely encountered and comprise 1-3% of gallbladder cancer cases. Pure squamous cell carcinoma of the gallbladder is rarer with l... 3/9/2018
Mohit Girotra, Kaartik Soota, Amaninder S Dhaliwal, Rtika R Abraham, Mauricio Garcia-Saenz-de-Sicilia, Benjamin Tharian Utility of endoscopic ultrasound and endoscopy in diagnosis and management of hepatocellular carcinoma and its complications What does endoscopic ultrasonography offer above and beyond conventional cross-sectional imaging Hepatocellular carcinoma constitutes over 90% of the primary liver tumors, the rest being cholangiocarcinoma. It has an insidious presentation, which is responsible for the delayed presentation. Hence, the management strategy relies on screening to diagnose it an early stage for curative resection a... 2/23/2018
Nayana George, Minjun Chen, Nancy Yuen, Christine M Hunt, Ayako Suzuki Interplay of gender, age and drug properties on reporting frequency of drug-induced liver injury We examined the effect of gender, age, and drug properties on liver events reporting frequency (RF) to assess patient- and drug-related risks for drug-induced liver injury (DILI). We performed a data-mining analysis of the WHO VigiBase™ to 1) identify drugs with gender- and age-biased RF and 2) char... 2/7/2018
Nayana George, Sherrie M Harrell, Kimberly D Rhodes, Andres Duarte-Rojo Recreational Drug and Psychosocial Profile in Chronic Hepatitis C Patients Seeking Antiviral Therapy CONCLUSION: Substance abuse is highly prevalent among HCV patients, and it is difficult to tell prior from current users. Integral care of HCV patients should include a diligent screen for substance abuse and rehabilitation referral, aiming to increase the pool of patients eligible for antiviral the... 1/10/2018
Nayana George, Abhilash Perisetti, Saikiran Raghavapuram, Debdeep Banerjee, Enoch Kuo, Benjamin Tharian Metastatic duodenal germ cell tumor diagnosed with endoscopic ultrasound No abstract 11/11/2017
Abhilash Perisetti, Nayana George, Saikiran Raghavapuram, Abu Baker Sheikh, Mohit Girotra, Benjamin Tharian Endoscopic Dissolution of Gastric Lipoma with Argon Plasma Coagulation A 47-year-old patient presented from outside the hospital for evaluation of iron deficiency anemia (IDA). The endoscopic workup suggested a gastric antral subepithelial lesion with an overlying arteriovenous malformation (AVM). Endoscopic ultrasound (EUS) revealed the lesion to be a lipoma. Given th... 10/5/2017
Abhilash Perisetti, Saikiran Raghavapuram, Benjamin Tharian Pearly Esophageal Papules An Innocent Bystander in the Evaluation of Dysphagia No abstract 9/16/2017
Abhilash Perisetti, Debdeep Banerjee, Benjamin Tharian Endoscopic Resection of Esophageal Mucosal Bridge No abstract 9/14/2017
Abhilash Perisetti, Saikiran Raghavapuram, Benjamin Tharian Cholelithiasis in a Patient With History of Cholecystectomy No abstract 9/6/2017
Nayana George, Saikiran Raghavapuram, Benjamin Tharian Widefield Endoscopic Mucosal Resection for Treatment of Proximal Esophageal Leukoplakia No abstract 8/15/2017
Nayana E George, Saikiran Raghavapuram, Debdeep Banerjee, Mohammad Al-Shoha, Faysal Fedda, Benjamin Tharian Ectopic Hepatocellular Carcinoma within a Choledochal Cyst Diagnosed Using Single-Operator Digital Cholangioscopy No abstract 8/3/2017
Ragesh Babu Thandassery, Saad Al Kaabi, Madiha E Soofi, Benjamin Tharian, Rajvir Singh Noninvasive serum models to predict significant liver related events in chronic hepatitis C CONCLUSIONS: Some simple pretreatment blood parameters and NIFS showed high accuracy for predicting development of SLRE post treatment. Application of these simple scores can improve assessment of long-term liver prognosis for CHC. 6/22/2017
Saad Khan, Nayana George, Benjamin Tharian Extraluminal migration of an esophageal metal stent causing splenic injury No abstract 10/15/2016
Saikiran Raghavapuram, Mohit Girotra, Jeffrey D Robertson, Tarun Pandey, Benjamin Tharian Successful management of ischemic cholangiopathy after failed endoscopicpercutaneous interventions, facilitated by digital cholangioscopy No abstract 7/25/2016
Mohit Girotra, Saikiran Raghavapuram, Benjamin Tharian Successful removal of deeply migrated pancreatic stent using biliary dilation balloon and the new single-operator digital cholangioscope No abstract 7/25/2016
Nayana George, Saad Khan, Emi Khoo, Tariq Masood, Benjamin Tharian Watch Your Speed-A Traumatic Case of Budd-Chiari Syndrome No abstract 7/1/2016
Benjamin Tharian, Nayana George, Udayakumar Navaneethan Endoscopy in the Diagnosis and Management of Complications of Inflammatory Bowel Disease The role of endoscopy in inflammatory bowel disease (IBD) has grown over the last decade in both diagnostic and therapeutic realms. It aids in the initial diagnosis of the disease and also in the assessment of the extent and severity of disease. IBD is associated with development of multiple complic... 12/31/2015
Nevin Yilmaz, Arife Zeybek, Benjamin Tharian, Ugur Eser Yilmaz Efficacy of nonsurgical tigecycline pleurodesis for the management of hepatic hydrothorax in patients with liver cirrhosis Chemical pleurodesis is one of the therapeutic tools to control hepatic hydrothorax. Tetracycline and derivatives have been widely accepted as an effective and safe treatment for the purpose, but availability is the big concern. Tigecycline is an antibiotic derivative of tetracycline, which has demo... 9/15/2015
Benjamin Tharian, Shyam Varadarajulu, Robert Hawes Drainage of obstructed gallbladder with use of lumen-apposing metal stent No abstract 8/18/2015
Benjamin Tharian, Nayana Elizabeth George, Tony Chiew Keong Tham What is the current role of endoscopy in primary sclerosing cholangitis Endoscopy has important roles in the management of primary sclerosing cholangitis (PSC), ranging from narrowing down the differential diagnoses, screening for complications, determining prognosis and therapy. While the need for a diagnostic endoscopic retrograde cholangiopancreatography (ERCP) may b... 8/13/2015
Bronte A Holt, Robert Hawes, Muhammad Hasan, Ashley Canipe, Benjamin Tharian, Udayakumar Navaneethan, Shyam Varadarajulu Biliary drainage role of EUS guidance CONCLUSIONS: In a tertiary-care center, use of advanced ERCP techniques results in a high technical success rate. EUS-guided biliary drainage was required in only 0.6% of native papilla ERCPs, and although a number of excellent indications exist, it should not replace good ERCP technique. 7/29/2015
Benjamin Tharian, Ashley Canipe, Udhaykumar Navaneethan, Shyam Varadarajulu, Robert Hawes, Muhammad Hasan Successful removal of a foreign body from a gallbladder remnant by using a new single-operator digital cholangioscope No abstract 7/29/2015
Muhammad Hasan, Ashley Canipe, Benjamin Tharian, Udhaykumar Navaneethan, Shyam Varadarajulu, Robert Hawes Digital cholangioscopy-directed removal of a surgical staple from a strictured bile duct No abstract 6/29/2015
Bronte A Holt, Gareth Hearn, Robert Hawes, Benjamin Tharian, Shyam Varadarajulu Development and evaluation of a 3D printed endoscopic ampullectomy training model with video CONCLUSION: Although further studies are necessary for validation, this novel prototype appears useful for endoscopic ampullectomy training. 5/20/2015
Vennisvasanth Lourdusamy, Benjamin Tharian, Udayakumar Navaneethan Biomarkers in bile-complementing advanced endoscopic imaging in the diagnosis of indeterminate biliary strictures Biliary strictures present a diagnostic challenge and a conundrum, particularly when an initial work up including abdominal imaging and endoscopic retrograde cholangiopancreatography based sampling are non-diagnostic. Advances in endoscopic imaging have helped us diagnose these strictures better. Ho... 4/23/2015
Benjamin Tharian, Ashley L Canipe, Konrad Krall, Robert H Hawes, Shantel Hébert-Magee Ring around the ROSE pancreatic acinar cell carcinoma diagnosed on site by EUS-FNA No abstract 3/26/2015
Avik Majumdar, Martin B Delatycki, Peter Crowley, Julie Lokan, Benjamin Tharian, Peter W Angus, Paul Gow An autosomal dominant form of non-cirrhotic portal hypertension No abstract 3/23/2015
Arpit Talwar, Nayana George, Benjamin Tharian, James Roberts-Thomson An immunosuppressed man with an aortic rupture secondary to Salmonella aortitis successfully treated with endovascular aortic repair A 75-year-old immunosuppressed man presented with fever and central abdominal pain 3 weeks after having positive blood cultures for Salmonella enteritidis. A computed tomography scan demonstrated a contained perforation of a nonaneurysmal abdominal aorta. Salmonella aortitis was suspected, and given... 2/28/2015
Benjamin Tharian, N George, J Turkington, G R Caddy Hoarseness and hematemesis a deadly combination No abstract 2/6/2014
Benjamin Tharian, Grant Caddy, Tony Ck Tham Enteroscopy in small bowel Crohns disease A review Crohn's disease (CD) is a chronic inflammatory condition of the gastrointestinal tract resulting in inflammation, stricturing and fistulae secondary to transmural inflammation. Diagnosis relies on clinical history, abnormal laboratory parameters, characteristic radiologic and endoscopic changes with... 10/23/2013
Benjamin Tharian, Fotios Tsiopoulos, Nayana George, Salvatore Di Pietro, Fabia Attili, Alberto Larghi Endoscopic ultrasound fine needle aspiration Technique and applications in clinical practice Since its initial report in 1992, endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has now been incorporated into the diagnostic and staging algorithm for the evaluation of benign and malignant diseases of the gastrointestinal tract and of adjacent organs. Its introduction constitutes a... 1/8/2013